IMMUNOENGINEERING LAB

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background behind the research

Taking Neutrophils to their Limit

• Neutrophils, a type of immune cell, are well known for their role in fighting pathogens
• In addition, neutrophils have been found to be involved in many inflammatory disorders such as in arthritis, certain cancers, diabetes, and even in responses against biomaterial implants

Questions we ask about their roles include:
1. How quickly are they produced by the body in response to an inflammatory stimulus?
2. What happens when the body faces two inflammatory disorders simultaneously?
3. How do opportunistic pathogens overcome neutrophil action?

Ultimate Goal:
Contribute towards understanding neutrophil actions in diseased conditions so new therapeutics may be developed.

Time-frame: Basic research with open goals and time-frames.

Vision: To create and enable technologies
that solve clinical problems associated with
immune responses
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Recent Posts

20. Cholesterol Levels and Monocyte Phenotype are Predictors of Non-healing in Individuals with Low Grade Diabetic Foot Ulcers: A Prospective Cohort Study

19. Sterile Inflammation Alters Neutrophil Kinetics in Mice.

Contact Info

  • Indian Institute of Science
  • Centre for BioSystems Science and Engineering
  • IISc, Bengaluru - 560012
  • siddharth [at] iisc [dot] ac [dot] in
  • +91 80 22932452

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